28 Jul 2015 Secondary Osteoporosis can be caused by certain medical conditions and medications that can Osteoporosis: Detection and Diagnosis
5 Mar 2021 men have a higher prevalence of secondary osteoporosis (60%) including exact mechanism depends on presence of nitrogen on alkyl chain
A rational search for the underlying disease or the bone-damaging medication is indicated particularly in adolescents, premenopausal women, men and postmenopausal women with rapidly decreasing bone tissue. Direct inhibitory effect of glucocorticoid (GC) on bone formation and promotion of apoptosis of bone cells are thought to be the major mechanism of glucocorticoid-induced osteoporosis (GIO). GC reduces not only bone mineral density (BMD) but also bone quality, therefore, patients with GIO have a higher risk of fracture than those with postmenopausal osteoporosis with the same level of BMD. The pathogenesis of secondary osteoporosis is almost always multifactorial. Certain endocrinopathies, systemic diseases, malignant neoplasias, organ dysfunctions, a variety of medications such as corticosteroids, lifestyle conditions and habits, and also major depression can lead to the secondary osteoporosis.
2011 Apr;51(4):307-24. doi: 10.1007/s00117-011-2143-9. [Secondary osteoporosis: pathogenesis, types, diagnostics and therapy]. [Article in German] The causes of secondary osteoporosis are numerous, and an understanding of their characteristics with respect to bone density and potential fracture risk is essential in the management of osteoporosis. A heightened awareness of the possibility of their existence is necessary to provide optimal care. The following is an organ-system based review of the pathogenesis and diagnostic considerations of the more common causes of secondary osteoporosis.
[Article in Japanese] Author Secondary osteoporosis can be caused by an identifiable agent such as glucocorticoids, or by a disease such as hyperthyroidism or myeloma. Although there are many causes of osteoporosis, the most common cause is oestrogen deficiency in postmenopausal women [3-5].
18 Oct 2015 Osteoporosis - overview. Thin bones; Low bone density; Metabolic bone disease; Hip fracture - osteoporosis; Compression fracture -
However, in some cases, 13 May 2016 Secondary Osteoporosis develops when certain medical conditions and medications increase bone remodeling leading to disruption of bone Secondary osteoporosis results from a variety of identifiable conditions that may include: (Sweet et al, Diagnosis of osteoporosis is made by three methods:. The mechanism of CIOP is uncertain but appears different from that of post‐ menopausal osteoporosis.
18 Oct 2015 Osteoporosis - overview. Thin bones; Low bone density; Metabolic bone disease; Hip fracture - osteoporosis; Compression fracture -
Cx37 C1019T Polymorphism May Contribute to the Pathogenesis of Polymorphisms in the 5' flank of COL1A1 gene and osteoporosis: osteoporosis. 3.
av M Pettersson · 2019 — will also be compared with postmortem diagnosis, to establish how often correct clinical diagnosis is made. Most of the culled Osteoporosis International, 22(6), ss. 2003-2006. osteogenesis of secondary centers of ossification.
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acute compression fracture or who present with a di agnosis of osteoporosis by BMD measurement. The most common causes of secondary osteoporosis in women are primary hyperparathyroidism and glucocorticoid use.
MAJOR (4): secondary bacterial infection may also occur e.g. cellulitis.
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Secondary causes of bone loss are not often considered in patients who are diagnosed as having osteoporosis. In some studies, 20% to 30% of postmenopausal women and more than 50% of men with osteoporosis have a secondary cause. There are numerous causes of secondary bone loss, includ-ing adverse effects of drug therapy, endocrine disorders,
Osteoporosis, a major public health problem, is becoming increasingly Secondary osteoporosis is associated with a number of. The extent to which these measurements predict fracture risk in the secondary forms of osteoporosis that are considered here is much less certain. In CKD and 1 Dec 2020 Pathogenesis of Osteoporosis in Rheumatoid Arthritis. RA is a the effect of zoledronic acid on secondary osteoporosis in 66 RA patients (69). Osteoporosis is characterized by low bone mass and microarchitectural we focus on the involvement of immune system in the pathogenesis of osteoporosis with of woman, there are many causes of secondary osteoporosis which occurs in The underlying pathophysiology of secondary osteoporosis involves the balance between resorption and formation of bone tissue through the process of bone causing a negative balance of calcium metabolism and a secondary hyperparathyroidism [1-8].
2015-04-21 · The pathogenesis of primary osteoporosis is complex and influenced by both environmental and genetic factors. Oxidative stress, apoptosis, sex-steroid deficiency and macroautophagy are age-related
Diagnosis & tre 14 Sep 2017 Osteoporosis lecture on the treatment, symptoms, pathophysiology, prevention, and nursing care (NCLEX review lecture).
2010-12-16 · Secondary causes of osteoporosis are present in about 30% of women and 55% of men with vertebral crush fractures Tests to exclude secondary causes include full blood count and erythrocyte sedimentation rate, bone biochemistry (serum calcium, phosphate, and alkaline phosphatase concentrations), liver and kidney function tests, serum thyroid stimulating hormone, and coeliac serology Secondary osteoporosis plays an important role in the pathogenesis of hip and spine fractures, but relatively little is known about the potential impact of secondary osteoporosis and fall-related disorders on the risk of distal forearm fractures. Osteoporosis in liver disease: pathogenesis and management Gabriela Handzlik-Orlik, Michał Holecki, Krzysztof Wilczyński and Jan Duława Abstract: Osteoporosis affects a substantial proportion of patients with chronic liver disease. Pathologic fracture in osteoporosis significantly affects quality of life and life expectancy. 2011-06-29 · The pathogenesis, diagnosis, investigation and management of osteoporosis Sunita K Sandhu,1 Geeta Hampson1,2 ABSTRACT With an increasingly ageing population, osteoporosis and osteoporosis-related fractures is fast becoming an important public health problem placing a considerable economic burden on health service resources. This does Osteoporosis is an important and often overlooked problem in men.